The main objective of this PhD project is the investigation of the antimicrobial activity of elastomeric liquid silicon materials. Since those are of primary interest for biomedical applications, two approaches will be carried out in parallel.
– The investigation of antimicrobial activity will be conducted in physiological—like conditions on model surfaces to achieve a comprehensive understanding of the role of materials physical properties, in particular elasticity, on protein adsorption and on bacterial adhesion. The effect of the physiological milieu on the materials properties will be evaluated in a second stage.
– A similar approach will be adopted to study antimicrobial activity on devices processed by injection to correlate outcomes gathered with both model surfaces and devices of interest for the biomedical industry.