The design of smart biomaterials is of importance for applications in biomedicine such as materials with antimicrobial activities, tissue engineering and drug delivery. Thermoresponsive polymers have gain attention in this field due to their ability to respond to temperature leading to a sharp change in properties. Two types of thermoresponsive polymers exist: those exhibiting a lower critical solution temperature (LCST) such as poly(N-isopropyl-acrylamide) and those presenting an upper critical solution temperature (UCST) such as poly(acrylamide-co-acrylonitrile). The project will aim at developing arginine-based polymers possessing antimicrobial and thermoresponsive properties. The doctoral work will involve the synthesis of the monomers and their polymerization, but also the investigation of their physico-chemical properties.

Publié le 07/07/2019