Le réseau

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L'organisation

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La structure de veille et de réflexion prospective

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Actualités

 

Zwitterions : la solution « Goldilocks » pour des implants sans caillots

Des chercheurs de l’Université de Sydney explorent l’utilisation de revêtements zwitterioniques pour prévenir la formation de caillots sanguins sur les implants médicaux, notamment les valves cardiaques et les stents. Ces molécules, naturellement présentes dans les membranes cellulaires, possèdent à la fois une charge positive et négative, ce qui leur confère une neutralité globale et une forte affinité pour l’eau. En créant un mince revêtement de quelques nanomètres, les scientifiques parviennent à générer une couche d’eau protectrice à la surface des implants. Cette « armure aqueuse » empêche l’adhérence des protéines du sang, réduisant ainsi le risque de thrombose, tout en améliorant la longévité des dispositifs implantables. Le défi, qualifié de « problème Goldilocks », consiste à déterminer la quantité idéale de zwitterions à appliquer, ni trop, ni trop peu, pour optimiser leur efficacité sans provoquer d’effets indésirables. Les travaux, publiés dans Cell Biomaterials (DOI : 10.1016/j.celbio.2024.100005), offrent un plan détaillé pour le développement de surfaces anti-caillots et ouvrent de nouvelles perspectives pour la conception d’implants plus sûrs et durables.
https://www.eurekalert.org/news-releases/1074179

Mycofluid : une alternative compostable aux plastiques grâce aux résidus de café et aux spores de Reishi

Des chercheurs de l’Université de Washington ont développé un procédé innovant permettant de transformer les marc de café usagés en une pâte biodégradable, baptisée « Mycofluid ». Cette pâte, obtenue en mélangeant marc de café, farine de riz complet, spores de champignon Reishi, gomme xanthane et eau, est utilisée pour l’impression 3D d’objets. Après impression, les pièces sont inoculées avec des spores de Reishi, qui forment une fine couche de mycélium – un réseau ressemblant à des racines – enveloppant les structures imprimées. Ce revêtement mycélien confère aux objets une résistance comparable à celle du polystyrène expansé, tout en étant entièrement compostable. Idéal pour remplacer des emballages tels que le Styrofoam, ce procédé offre une solution personnalisable et durable pour les petites productions, notamment pour des emballages sur mesure destinés aux petites entreprises.

https://www.eurekalert.org/news-releases/1074113

Revêtement transparent superhydrophile pour séparation durable huile/eau

Des chercheurs ont développé un revêtement innovant, intégrant une interphase inspirée par les moules et une couche composite double constituée de nanofibres de cellulose rigides et de carbonate de calcium amorphe, permettant de créer une surface superhydrophile aux propriétés anti-encrassement par huile exceptionnellement persistantes sur divers substrats. Ce revêtement, grâce à l’interconnexion étroite entre l’intercouche adhésive et la couche externe hautement hydratée, empêche efficacement l’encrassement par divers types d’huile, que ce soit dans des environnements pré-humidifiés ou déjà contaminés, garantissant ainsi une séparation efficace et durable des émulsions huile/eau sans déclin significatif du flux, avec un taux de récupération du flux proche de 100 %. De plus, le revêtement présente des propriétés antifogging et une grande transparence, ouvrant la voie à des applications potentielles dans des dispositifs optiques, tout en répondant aux besoins d’une séparation à long terme dans des conditions industrielles sévères.

https://pubs.acs.org/doi/10.1021/acs.langmuir.4c05307

Hydrogels d’ADN innovants pour une libération prolongée de médicaments

Des chercheurs de l’Université de Tokyo ont développé des hydrogels d’ADN optimisés à partir de nanostructures en forme de Takumi, minimisées pour n’utiliser que deux oligonucléotides (ODN) par unité, soit seulement 68 nucléotides au total. Cette approche, détaillée dans le Journal of Controlled Release (DOI : 10.1016/j.jconrel.2024.11.052), permet de former des hydrogels biocompatibles et injectables présentant une rétention prolongée in vivo, comme démontré par des expériences chez la souris où le gel contenant de la doxorubicine a persisté au moins 168 heures et induit des effets antitumoraux significatifs. En réduisant les coûts de préparation et le risque d’effets hors cible par rapport aux méthodes antérieures (par exemple, les hydrogels à base de hexapodna), cette stratégie promet d’améliorer l’efficacité des systèmes de délivrance de médicaments et d’ouvrir la voie à des applications dans la libération ciblée d’antigènes et d’autres biomolécules.
https://www.eurekalert.org/news-releases/1073422

Nanoplastiques sur glaciers alpins : une étude révélatrice

Des chercheurs du Centre Helmholtz pour la Recherche Environnementale – UFZ, en collaboration avec des alpinistes expérimentés, ont détecté des particules plastiques nanométriques sur des glaciers alpins situés à plus de 3 000 m d’altitude. En collectant des échantillons de neige et de glace à 14 sites en France, en Italie et en Suisse, l’équipe a utilisé un spectromètre de masse à transfert de protons couplé à une désorption thermique pour identifier les plastiques présents. Les analyses ont révélé la présence principalement de polyéthylène et de polystyrène, avec une empreinte liée à l’usure des pneus, tandis que le PET était beaucoup moins fréquent. Les concentrations mesurées variaient entre 2 et 80 ng/ml dans la neige fondue, indiquant une distribution hétérogène due aux conditions locales, notamment la force du vent qui redistribue les particules. Par ailleurs, un modèle de dispersion atmosphérique (Flexpart) a permis d’identifier les sources probables des nanoplastiques, majoritairement provenant de l’Atlantique, ainsi que de la France, de l’Espagne et de la Suisse. Ce travail, publié dans Scientific Reports (DOI : 10.1038/s41598-024-84210-9), souligne l’importance de comprendre la dispersion globale des plastiques et ouvre la voie à un projet de science citoyenne, GAPS 2024, visant à étendre l’étude des nanoplastiques sur les glaciers à l’échelle mondiale.

https://www.eurekalert.org/news-releases/1073596

Méthode écologique de séparation et de recyclage des réfrigérants

Des chercheurs de l’Université du Kansas, menés par la doctorante Abby Harders dans le groupe du professeur Mark Shiflett, ont mis au point une méthode innovante reposant sur des membranes en polymères fluorés amorphes pour séparer efficacement les mélanges complexes de réfrigérants, en particulier les hydrofluorocarbures (HFC) dont l’émission contribue fortement au réchauffement climatique. Grâce à un procédé de revêtement personnalisé qui permet la fabrication de fibres creuses composites dotées de couches submicroniques sur supports poreux, cette technologie optimise la séparation des composants gazeux, surpassant ainsi les limites des méthodes traditionnelles telles que la distillation. Cette approche est particulièrement pertinente dans le contexte des réglementations internationales, notamment l’amendement de Kigali et l’American Innovation and Manufacturing Act, qui visent à réduire progressivement la production et l’émission des HFC, tels que le HFC-134a, dont le potentiel de réchauffement est 1 430 fois supérieur à celui du CO₂. En facilitant la récupération, la purification et la réintroduction des réfrigérants sur le marché, la méthode proposée offre une solution économiquement viable pour prévenir la libération massive de ces gaz en fin de vie des équipements. Publiée dans Science Advances, cette recherche ouvre de nouvelles perspectives pour le recyclage industriel des réfrigérants, contribuant ainsi à la réduction de l’empreinte carbone du secteur et à la transition vers une économie circulaire.

https://phys.org/news/2025-02-eco-friendly-method-recycle-refrigerants.html

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Adhérez au GFP

Devenez un membre et découvrez les avantages d’un abonnement GFP.

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Sections locales GFP

Lorem ipsum dolor sit amet, consectetur adipiscing elit. Etiam feugiat quis risus quis tempus. Morbi pharetra volutpat ligula ut placerat. Morbi sagittis ornare tellus, at molestie urna suscipit id. Praesent non est quis ante pretium ullamcorper. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Vestibulum ante ipsum primis in faucibus orci luctus et ultrices posuere cubilia Curae; Integer sodales nisi justo, a varius nisi viverra accumsan. Quisque eleifend velit sed suscipit convallis. Donec ac facilisis massa. Donec euismod erat molestie nisi condimentum mattis. Nunc eu eros lacinia, vestibulum nibh vitae, varius magna. Aliquam erat volutpat. Suspendisse potenti.

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