Le réseau
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L'organisation
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La structure de veille et de réflexion prospective
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Actualités
L’intelligence artificielle accélère la formulation de polymères médicaux
Une nouvelle plateforme d’analytique prédictive basée sur l’IA révolutionne la mise au point des polymères destinés aux dispositifs médicaux. Développée par ChemInformatics Inc., cette technologie utilise l’apprentissage automatique pour modéliser la relation structure–propriété des polymères à partir de vastes bases de données expérimentales. En simulant instantanément les effets de la composition, de la masse molaire et des additifs, elle réduit les temps de formulation de plusieurs mois à quelques jours. L’outil permet de prédire la biocompatibilité, la résistance mécanique ou la stabilité chimique avant toute synthèse en laboratoire. Cette approche intégrée pourrait transformer le développement de polymères médicaux sur mesure, en combinant durabilité, performance et conformité réglementaire grâce à la convergence entre science des matériaux et intelligence artificielle.
Endoprothèse coronaire bioresorbable amorphe PLLA/PLGA : une cicatrisation vasculaire optimisée
Des chercheurs polonais ont mis au point un nouveau stent bioresorbable en copolymère amorphe PLLA/PLGA (Apollo, Biostent Consortium) testé chez le porc. Par rapport aux stents cristallins classiques, ce matériau réduit de 7,2 fois l’inflammation locale et induit un remodelage vasculaire positif avec agrandissement de la lumière après 90 jours. L’amorphisation et la part de PLGA accélèrent la dégradation tout en maintenant la rigidité radiale, favorisant une guérison homogène et une réendothélialisation complète. Ce prototype marque une avancée vers des stents de nouvelle génération conciliant biocompatibilité, performance mécanique et résorption contrôlée.
Nature Vers une chimie circulaire du polystyrène grâce aux trithiocarbonates
Des chercheurs japonais ont mis au point un polymère décomposable et recyclable à base de polystyrène fonctionnalisé par des groupes trithiocarbonate. Ce matériau se désagrège à température ambiante sous l’action de l’allylamine, perdant toute cohésion en 96 heures, puis peut être régénéré par une réaction thiol-ène sous irradiation UV (365 nm). Basée sur la chimie RAFT, cette approche introduit des liaisons dynamiques permettant un cycle chimique fermé. Elle ouvre la voie à une nouvelle génération de plastiques intégrant dès leur conception des fonctions de dépolymérisation et de revalorisation contrôlée.
Nature L’entropie topologique appliquée aux polymères : une approche mathématique prédictive
Des chercheurs ont exploité la théorie des graphes pour quantifier la complexité structurale de polymères comme les polyesters et polycarbonates. En calculant divers indices topologiques (Zagreb, géométrico-arithmétique, connectivité atome-liaison) et leurs entropies de Shannon associées, ils ont établi un modèle de régression logarithmique reliant ces descripteurs à la désorganisation moléculaire. Cette approche mathématique permet de relier la structure chimique à des propriétés physicochimiques clés, ouvrant la voie à une prédiction fine des performances des matériaux polymères à partir de leur topologie moléculaire.
La cryo-tomographie révèle la dynamique des polymères photo-résistants pour une lithographie sans défauts
Des chercheurs chinois ont utilisé la cryo-tomographie électronique pour reconstruire en 3D le comportement des polymères photo-résistants dans un film liquide, étape clé du développement des circuits intégrés. Cette méthode révèle pour la première fois l’organisation et les enchevêtrements moléculaires au niveau de l’interface air-liquide, responsables de nombreux défauts de motifs. En optimisant ces interactions, les auteurs ont supprimé plus de 99 % des contaminations sur des plaquettes de 12 pouces, ouvrant la voie à une lithographie industrielle plus précise et compatible avec les procédés de fabrication avancés.
Nature Renforcer les bioplastiques de soja grâce à une ingénierie bio-inspirée
Des chercheurs de l’Université Washington à St. Louis ont mis au point une méthode innovante pour améliorer considérablement les performances mécaniques des bioplastiques à base de protéines de soja et de cellulose. Ces polymères naturels, proposés comme alternatives aux plastiques pétrosourcés, souffrent souvent de fragilité et de faible résistance. L’équipe de Marcus Foston a montré que le revêtement des nanocristaux de cellulose par une fine couche de polydopamine — molécule inspirée des adhésifs marins des moules — modifie l’interface entre phases et accroît la cohésion du matériau. Cette modification de surface optimise les interactions entre la matrice protéique et le renfort cellulosique, multipliant par plus de 300 % la résistance à la traction et la flexibilité du composite. Cette approche, décrite dans Polymer Composites, démontre que les biopolymères issus de ressources végétales peuvent être structurellement optimisés pour rivaliser avec les polymères fossiles, ouvrant la voie à une nouvelle génération de matériaux biosourcés performants et durables.
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Adhérez au GFP
Devenez un membre et découvrez les avantages d’un abonnement GFP.
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Sections locales GFP
Lorem ipsum dolor sit amet, consectetur adipiscing elit. Etiam feugiat quis risus quis tempus. Morbi pharetra volutpat ligula ut placerat. Morbi sagittis ornare tellus, at molestie urna suscipit id. Praesent non est quis ante pretium ullamcorper. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Vestibulum ante ipsum primis in faucibus orci luctus et ultrices posuere cubilia Curae; Integer sodales nisi justo, a varius nisi viverra accumsan. Quisque eleifend velit sed suscipit convallis. Donec ac facilisis massa. Donec euismod erat molestie nisi condimentum mattis. Nunc eu eros lacinia, vestibulum nibh vitae, varius magna. Aliquam erat volutpat. Suspendisse potenti.
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Les partenaires
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lrccp
http://www.ispa.asso.fr
logo-ispa_coul_fond-fonce
http://www.ispa.asso.fr
LPMC
http://www.ispa.asso.fr
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cnrs
http://www.ispa.asso.fr
hutchinson
http://www.hutchinson.com/fr
ICS
https://www-ics.u-strasbg.fr/
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http://www.waters.com
arkema
http://www.coatex.com
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