The objective of the present project is thus to develop medical grade bio-based polyglycolide with characteristics compatible with its use as resorbable sutures. This will be conducted in three steps dealing with: 1) development and screaming of suitable polymerization catalysts to get high molecular weights PGA; 2) the upscale of the reaction; 3) melt-spinning of the resulting bio-based PGA.

This work will be developed in collaboration with BKB Chemicals https://bkb-chemicals.com/ and three academic laboratories from the University of Lille UCCS, UMET and GEMTEX. The UCCS (Solid State Catalysis and Chemistry Unit, https://uccs.univ-lille.fr/) laboratory and in particular the CADICOM team will work specifically on the polymerization of bio-based glycolide at the lab scale, and thus the screening of catalysts that will be suitable for reactive processes at UMET. Then, ISP team of UMET (Materials and Transformations Unit, https://umet.univ-lille.fr/) laboratory will deal will the upscale of the polymerization of bio-based glycolide by reactive extrusion. Finally, the GEMTEX (Textile Materials Engineering, https://www.gemtex.fr/) laboratory at ENSAIT-Roubaix will afford its expertise in polymers and their processing (melt spinning and bulk and surface functionalization) required to design resorbable suture filaments.

Publié le 15/02/2026